Ventricular tachycardia storm leading to heart transplantation – a case report

    Authors

    Keywords

    ventricular tachycardia storm, ischemic cardiomyopathy, ablation, heart transplantation, nursing

    DOI

    https://doi.org/10.15836/ccar2025.280

    Full Text

    **Introduction**: Ventricular tachycardia (VT) storm represents one of the most challenging entities in invasive arrhythmology. In patients with advanced ischemic cardiomyopathy and multiple ablation attempts, refractory VT can necessitate advanced heart failure therapies including transplantation (1). **Case report**: 65-year-old male with ischemic cardiomyopathy, history of myocardial infarction, multiple coronary interventions, and ICD implantation was admitted with sustained VT. Despite repeated catheter ablations (2023, Feb 2025, May 2025), recurrent polymorphic VT persisted. During the last procedure, multiple inducible VTs were documented, including unstable morphologies resistant to ablation. Hemodynamic compromise required advanced support and multidisciplinary discussion. Right heart catheterization confirmed elevated filling pressures and reduced cardiac index (2.3 L/min/m2). Owing to recurrent VT storm, severely reduced LV function (EF ~30%), and aneurysmatic remodeling, the patient was referred for urgent transplant evaluation. Comprehensive pre-transplant screening (dental, dermatological, urological, infectious, psychiatric) revealed no contraindications. On 13 June 2025, urgent orthotopic heart transplantation with ICD extraction was performed. The postoperative course was uneventful; the patient was weaned early from ventilation, mobilized within days, and later discharged on triple immunosuppressive therapy. Follow-up myocardial biopsies demonstrated no significant rejection (ISHLT 0–1R). **Conclusion**: This case illustrates the complexity of VT storm in end-stage ischemic cardiomyopathy and the ultimate role of heart transplantation. Successful management required coordinated work of arrhythmia specialists, heart failure cardiologists, intensivists, cardiac surgeons, and highly skilled nursing teams across cardiology and cardiac surgery. Nurses were integral in arrhythmia monitoring, advanced device management, perioperative care, and post-transplant education, highlighting the multidimensional role of nursing in one of the most complex areas of contemporary cardiology.

    Literature

    1. Zeppenfeld K, Tfelt-Hansen J, de Riva M, Winkel BG, Behr ER, Blom NA, et al. 2022 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death. Eur Heart J. 2022 October 21;43(40):3997–4126. https://doi.org/10.1093/eurheartj/ehac262
    Cardiologia Croatica
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    Ventricular tachycardia storm leading to heart transplantation – a case report

    Extended Abstract
    Issue11-12
    Published
    Pages280
    PDF via DOIhttps://doi.org/10.15836/ccar2025.280
    ventricular tachycardia storm
    ischemic cardiomyopathy
    ablation
    heart transplantation
    nursing

    Authors

    Josipa Pekez*ORCIDDubrava University Hospital, Zagreb, Croatia
    Zrinka PaićORCIDDubrava University Hospital, Zagreb, Croatia
    Julija BuljanORCIDDubrava University Hospital, Zagreb, Croatia
    Nikolina ValjakORCIDDubrava University Hospital, Zagreb, Croatia
    Anita PleškoORCIDDubrava University Hospital, Zagreb, Croatia
    Ivica BenkoORCIDDubrava University Hospital, Zagreb, Croatia

    *Correspondence email: joshiiii2000@gmail.com

    Full Text

    Introduction: Ventricular tachycardia (VT) storm represents one of the most challenging entities in invasive arrhythmology. In patients with advanced ischemic cardiomyopathy and multiple ablation attempts, refractory VT can necessitate advanced heart failure therapies including transplantation (1).

    Case report: 65-year-old male with ischemic cardiomyopathy, history of myocardial infarction, multiple coronary interventions, and ICD implantation was admitted with sustained VT. Despite repeated catheter ablations (2023, Feb 2025, May 2025), recurrent polymorphic VT persisted. During the last procedure, multiple inducible VTs were documented, including unstable morphologies resistant to ablation. Hemodynamic compromise required advanced support and multidisciplinary discussion. Right heart catheterization confirmed elevated filling pressures and reduced cardiac index (2.3 L/min/m2). Owing to recurrent VT storm, severely reduced LV function (EF ~30%), and aneurysmatic remodeling, the patient was referred for urgent transplant evaluation. Comprehensive pre-transplant screening (dental, dermatological, urological, infectious, psychiatric) revealed no contraindications. On 13 June 2025, urgent orthotopic heart transplantation with ICD extraction was performed. The postoperative course was uneventful; the patient was weaned early from ventilation, mobilized within days, and later discharged on triple immunosuppressive therapy. Follow-up myocardial biopsies demonstrated no significant rejection (ISHLT 0–1R).

    Conclusion: This case illustrates the complexity of VT storm in end-stage ischemic cardiomyopathy and the ultimate role of heart transplantation. Successful management required coordinated work of arrhythmia specialists, heart failure cardiologists, intensivists, cardiac surgeons, and highly skilled nursing teams across cardiology and cardiac surgery. Nurses were integral in arrhythmia monitoring, advanced device management, perioperative care, and post-transplant education, highlighting the multidimensional role of nursing in one of the most complex areas of contemporary cardiology.

    Literature

    1. 1.
      Zeppenfeld K, Tfelt-Hansen J, de Riva M, Winkel BG, Behr ER, Blom NA, et al. 2022 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death. Eur Heart J. 2022 October 21;43(40):3997–4126.DOI