The role of echocardiography in differential diagnosis of cardiac sources of embolism

    Authors

    Abstract

    Stroke is a leading cause of morbidity and mortality. According to pathophysiologic mechanisms, stroke can be divided into two major groups: ischemic (85%) and hemorrhagic (15%). 20% of ischemic strokes are caused by cardiac embolisms. Brain imaging (CT, MR) confirms the diagnosis, some specific characteristics seen during the imaging of the brain may suggest a distinct cardiac cause. Clinical history, examination and electrocardiogram can shed light on a potential cardiac cause of ischemic stroke. Echocardiography is a key method in the evaluation, diagnosis and management of embolic stroke (transthoracic echo, transesophageal echo, 3D echo, contrast echo). The etiological factors of cerebrovascular events are: blood clots, tumor fragments, infected and noninfected vegetations, calcified particles, atherosclerotic debris. Cardiac sources of emboli can be divided according to embolic potential into a) **high risk**: intracardiac thrombi (atrial arrhythmias - atrial fibrillation, ischemic heart disease, non-ischemic cardiomyopathies, prosthetic valves and devices), intracardiac vegetations, intracardiac tumors, aortic atheroma; b) **low risk**: spontaneous echo contrast without clot, left ventricle aneurysm without clot, intracardiac calcifications, valvular anomalies, septal defects and anomalies. The indications for echocardiography in patients with neurological events are: abrupt occlusion of a major peripheral or visceral artery in patients of any age; younger patients with CV events (45 years) with neurologic events without evidence of cerebrovascular disease or other obvious cause, patients for whom a clinical therapeutic decision will depend on the results of echocardiography.

    Keywords

    cardiac embolism, echocardiography, stroke

    DOI

    https://doi.org/10.15836/ccar2017.145
    Cardiologia Croatica
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    The role of echocardiography in differential diagnosis of cardiac sources of embolism

    Extended Abstract
    Issue4
    Published
    Pages145
    PDF via DOIhttps://doi.org/10.15836/ccar2017.145
    cardiac embolism
    echocardiography
    stroke

    Authors

    Kristina Selthofer-Relatić*ORCIDUniversity Hospital Centre Osijek, Osijek, Croatia

    *Correspondence email: selthofer.relatic@gmail.com

    Abstract

    Stroke is a leading cause of morbidity and mortality. According to pathophysiologic mechanisms, stroke can be divided into two major groups: ischemic (85%) and hemorrhagic (15%). 20% of ischemic strokes are caused by cardiac embolisms. Brain imaging (CT, MR) confirms the diagnosis, some specific characteristics seen during the imaging of the brain may suggest a distinct cardiac cause. Clinical history, examination and electrocardiogram can shed light on a potential cardiac cause of ischemic stroke. Echocardiography is a key method in the evaluation, diagnosis and management of embolic stroke (transthoracic echo, transesophageal echo, 3D echo, contrast echo). The etiological factors of cerebrovascular events are: blood clots, tumor fragments, infected and noninfected vegetations, calcified particles, atherosclerotic debris. Cardiac sources of emboli can be divided according to embolic potential into a) **high risk**: intracardiac thrombi (atrial arrhythmias - atrial fibrillation, ischemic heart disease, non-ischemic cardiomyopathies, prosthetic valves and devices), intracardiac vegetations, intracardiac tumors, aortic atheroma; b) **low risk**: spontaneous echo contrast without clot, left ventricle aneurysm without clot, intracardiac calcifications, valvular anomalies, septal defects and anomalies. The indications for echocardiography in patients with neurological events are: abrupt occlusion of a major peripheral or visceral artery in patients of any age; younger patients with CV events (45 years) with neurologic events without evidence of cerebrovascular disease or other obvious cause, patients for whom a clinical therapeutic decision will depend on the results of echocardiography.