Authors
- Nejra Mlačo-Vražalić — General Hospital “Prim.dr.Abdulah Nakaš”, Sarajevo, Bosnia and Herzegovina — ORCID: 0000-0002-3299-6899
- Dino Alić — General Hospital “Prim.dr.Abdulah Nakaš”, Sarajevo, Bosnia and Herzegovina — ORCID: 0009-0001-5571-7426
- Lana Mrdović — Health Care Center Istočno Sarajevo, Istočno Sarajevo, Bosnia and Herzegovina — ORCID: 0009-0004-4046-9513
- Džana Badžak — Health Care Center Konjic, Konjic, Bosnia and Herzegovina — ORCID: 0009-0000-9655-5315
- Amela Sofić — General Hospital “Prim.dr.Abdulah Nakaš”, Sarajevo, Bosnia and Herzegovina — ORCID: 0000-0002-1577-1006
- Aida Mujaković — General Hospital “Prim.dr.Abdulah Nakaš”, Sarajevo, Bosnia and Herzegovina — ORCID: 0000-0002-0022-1482
- Tijana Muhić-Skalonja — General Hospital “Prim.dr.Abdulah Nakaš”, Sarajevo, Bosnia and Herzegovina — ORCID: 0009-0001-4717-8733
- Akif Mlačo — Clinical Center University of Sarajevo, Sarajevo, Bosnia and Herzegovina — ORCID: 0000-0002-1907-9017
- Denis Mačkić — General Hospital “Prim.dr.Abdulah Nakaš”, Sarajevo, Bosnia and Herzegovina — ORCID: 0000-0001-6540-4944
- Nejra Prohić — General Hospital “Prim.dr.Abdulah Nakaš”, Sarajevo, Bosnia and Herzegovina — ORCID: 0000-0001-6789-1096
- Ada Đozić — General Hospital “Prim.dr.Abdulah Nakaš”, Sarajevo, Bosnia and Herzegovina — ORCID: 0000-0002-2664-810X
- Adnan Mušanović — Clinical Center University of Sarajevo, Sarajevo, Bosnia and Herzegovina — ORCID: 0009-0007-3589-3848
- Jasmin Idrizović — General Hospital “Prim.dr.Abdulah Nakaš”, Sarajevo, Bosnia and Herzegovina — ORCID: 0009-0006-3598-3870
- Edin Begić — General Hospital “Prim.dr.Abdulah Nakaš”, Sarajevo, Bosnia and Herzegovina — ORCID: 0000-0001-6842-262X
Keywords
pulmonary embolism, CT angiography, D-dimer
DOI
https://doi.org/10.15836/ccar2024.495Full Text
**Introduction**: Obstruction of the pulmonary artery and its branches increases the pulmonary vascular resistance, resulting in pulmonary hypertension and right ventricular (RV) dysfunction. (1, 2) Aim: To analyze the correlation between the pulmonary artery obstruction index (PAOI) score obtained from quantifying obstruction in pulmonary embolism (PE), inflammatory markers, coagulation parameters, and echocardiographic findings. **Patients and Methods**: This retrospective study included 59 patients hospitalized with PE at the Department of Internal Medicine, General Hospital “Prim.dr. Abdulah Nakaš” in the period from 2022 until 2024. PE was confirmed on CT angiography and the PAOI score was calculated using the Qanadli index. Echocardiography was performed during hospitalization. Inflammatory and coagulation parameters were obtained. **Results**: The PAOI score significantly correlated with the right ventricular systolic pressure (RVSP) (p=0.03) and with the presence and degree of the tricuspid regurgitation (p=0.03). No correlation was found between the PAOI score and other echocardiographic parameters. Strong correlation was found between the PAOI score and D-dimer values (p<0.001). No significant correlation was found between the PAOI score and C-reactive protein, hemogram and hemogram-derived ratios. **Conclusion**: The PAOI score on admission in patients with PE is in correlation with RV function and coagulation parameters.
Literature
- Russell C, Keshavamurthy S, Saha S. Classification and Stratification of Pulmonary Embolisms. Int J Angiol. 2022 September 2;31(3):162–5. https://doi.org/10.1055/s-0042-1756218
- Hajiahmadi S, Tabesh F, Shayganfar A, Shirani F, Ebrahimian S. Pulmonary artery obstruction index, pulmonary artery diameter and right ventricle strain as prognostic CT findings in patient with acute pulmonary embolism. Radiologia (Engl Ed). 2023 May-June;65(3):200–12. https://doi.org/10.1016/j.rxeng.2021.04.001