The pulmonary artery obstruction index (PAOI) score is correlated with right ventricular systolic pressure, tricuspid regurgitation and D-dimer values in patients with pulmonary embolism

    Authors

    Keywords

    pulmonary embolism, CT angiography, D-dimer

    DOI

    https://doi.org/10.15836/ccar2024.495

    Full Text

    **Introduction**: Obstruction of the pulmonary artery and its branches increases the pulmonary vascular resistance, resulting in pulmonary hypertension and right ventricular (RV) dysfunction. (1, 2) Aim: To analyze the correlation between the pulmonary artery obstruction index (PAOI) score obtained from quantifying obstruction in pulmonary embolism (PE), inflammatory markers, coagulation parameters, and echocardiographic findings. **Patients and Methods**: This retrospective study included 59 patients hospitalized with PE at the Department of Internal Medicine, General Hospital “Prim.dr. Abdulah Nakaš” in the period from 2022 until 2024. PE was confirmed on CT angiography and the PAOI score was calculated using the Qanadli index. Echocardiography was performed during hospitalization. Inflammatory and coagulation parameters were obtained. **Results**: The PAOI score significantly correlated with the right ventricular systolic pressure (RVSP) (p=0.03) and with the presence and degree of the tricuspid regurgitation (p=0.03). No correlation was found between the PAOI score and other echocardiographic parameters. Strong correlation was found between the PAOI score and D-dimer values (p<0.001). No significant correlation was found between the PAOI score and C-reactive protein, hemogram and hemogram-derived ratios. **Conclusion**: The PAOI score on admission in patients with PE is in correlation with RV function and coagulation parameters.

    Literature

    1. Russell C, Keshavamurthy S, Saha S. Classification and Stratification of Pulmonary Embolisms. Int J Angiol. 2022 September 2;31(3):162–5. https://doi.org/10.1055/s-0042-1756218
    2. Hajiahmadi S, Tabesh F, Shayganfar A, Shirani F, Ebrahimian S. Pulmonary artery obstruction index, pulmonary artery diameter and right ventricle strain as prognostic CT findings in patient with acute pulmonary embolism. Radiologia (Engl Ed). 2023 May-June;65(3):200–12. https://doi.org/10.1016/j.rxeng.2021.04.001
    Cardiologia Croatica
    Back to search

    The pulmonary artery obstruction index (PAOI) score is correlated with right ventricular systolic pressure, tricuspid regurgitation and D-dimer values in patients with pulmonary embolism

    Extended Abstract
    Issue11-12
    Published
    Pages495
    PDF via DOIhttps://doi.org/10.15836/ccar2024.495
    pulmonary embolism
    CT angiography
    D-dimer

    Authors

    Nejra Mlačo-Vražalić*ORCIDGeneral Hospital “Prim.dr.Abdulah Nakaš”, Sarajevo, Bosnia and Herzegovina
    Dino AlićORCIDGeneral Hospital “Prim.dr.Abdulah Nakaš”, Sarajevo, Bosnia and Herzegovina
    Lana MrdovićORCIDHealth Care Center Istočno Sarajevo, Istočno Sarajevo, Bosnia and Herzegovina
    Džana BadžakORCIDHealth Care Center Konjic, Konjic, Bosnia and Herzegovina
    Amela SofićORCIDGeneral Hospital “Prim.dr.Abdulah Nakaš”, Sarajevo, Bosnia and Herzegovina
    Aida MujakovićORCIDGeneral Hospital “Prim.dr.Abdulah Nakaš”, Sarajevo, Bosnia and Herzegovina
    Tijana Muhić-SkalonjaORCIDGeneral Hospital “Prim.dr.Abdulah Nakaš”, Sarajevo, Bosnia and Herzegovina
    Akif MlačoORCIDClinical Center University of Sarajevo, Sarajevo, Bosnia and Herzegovina
    Denis MačkićORCIDGeneral Hospital “Prim.dr.Abdulah Nakaš”, Sarajevo, Bosnia and Herzegovina
    Nejra ProhićORCIDGeneral Hospital “Prim.dr.Abdulah Nakaš”, Sarajevo, Bosnia and Herzegovina
    Ada ĐozićORCIDGeneral Hospital “Prim.dr.Abdulah Nakaš”, Sarajevo, Bosnia and Herzegovina
    Adnan MušanovićORCIDClinical Center University of Sarajevo, Sarajevo, Bosnia and Herzegovina
    Jasmin IdrizovićORCIDGeneral Hospital “Prim.dr.Abdulah Nakaš”, Sarajevo, Bosnia and Herzegovina
    Edin BegićORCIDGeneral Hospital “Prim.dr.Abdulah Nakaš”, Sarajevo, Bosnia and Herzegovina

    *Correspondence email: nejra.ml@gmail.com

    Full Text

    Introduction: Obstruction of the pulmonary artery and its branches increases the pulmonary vascular resistance, resulting in pulmonary hypertension and right ventricular (RV) dysfunction. (1, 2) Aim: To analyze the correlation between the pulmonary artery obstruction index (PAOI) score obtained from quantifying obstruction in pulmonary embolism (PE), inflammatory markers, coagulation parameters, and echocardiographic findings.

    Patients and Methods: This retrospective study included 59 patients hospitalized with PE at the Department of Internal Medicine, General Hospital “Prim.dr. Abdulah Nakaš” in the period from 2022 until 2024. PE was confirmed on CT angiography and the PAOI score was calculated using the Qanadli index. Echocardiography was performed during hospitalization. Inflammatory and coagulation parameters were obtained.

    Results: The PAOI score significantly correlated with the right ventricular systolic pressure (RVSP) (p=0.03) and with the presence and degree of the tricuspid regurgitation (p=0.03). No correlation was found between the PAOI score and other echocardiographic parameters. Strong correlation was found between the PAOI score and D-dimer values (p<0.001). No significant correlation was found between the PAOI score and C-reactive protein, hemogram and hemogram-derived ratios.

    Conclusion: The PAOI score on admission in patients with PE is in correlation with RV function and coagulation parameters.

    Literature

    1. 1.
      Russell C, Keshavamurthy S, Saha S. Classification and Stratification of Pulmonary Embolisms. Int J Angiol. 2022 September 2;31(3):162–5.DOI
    2. 2.
      Hajiahmadi S, Tabesh F, Shayganfar A, Shirani F, Ebrahimian S. Pulmonary artery obstruction index, pulmonary artery diameter and right ventricle strain as prognostic CT findings in patient with acute pulmonary embolism. Radiologia (Engl Ed). 2023 May-June;65(3):200–12.DOI