The influence of anemia on repeated hospitalization in patients with heart failure and left ventricular systolic disfunction

    Authors

    Keywords

    anemia, iron deficiency, heart failure, hospitalization

    DOI

    https://doi.org/10.15836/ccar2018.354

    Full Text

    Zaključak: Anemija u bolesnika s KZS predstavlja značajni faktor loše prognoze te može uzrokovati učestalije hospitalizacije i preglede u hitnoj ambulanti. Kako liječenje čak i visokim dozama peroralnog željeza kod tih bolesnika nije dovelo do kliničkog poboljšanja uveden je novi protokol dokazano korisnog liječenja tih bolesnika visokodoznim intravenskim željezom. Introduction: Anemia is frequent in patients with chronic heart failure (CHF) and is connected to a worse prognosis, regardless the severity and type. The correction of anemia contributes to the improvement of health, which also reduces the number of hospitalizations, improves the survival rate and the quality of life. ( 1 - 3 ) Patients and Methods: This retrospective analysis includes patients with CHF and a reduced systolic function of the left ventricle who have been treated for the last three years at the Department of Cardiology University Hospital Centre “Sestre milosrdnice“ in Zagreb. The method of parallel sample was used to compare the data of a hundred patients with anemia and a hundred patients without anemia. Using the statistical analysis of multiple factors it was attempted to determine the influence of anemia as an independent risk factor in the number of repeated hospitalizations. Results: Although patients with anemia were older than those without anemia (median 77 (66-85): 67.5 (58-75.3); p <0.0001, Mann-Whitney), it was determined that patients with CHF and anemia were hospitalized more frequently than those who have CHF without anemia (median 4 (3-6):2 (1-4); p <0.0001, Mann-Whitney). Patients with anemia were more often examined in the unified urgent reception (median (4 (3-6): 2 (1-4); p <0.0001, Mann-Whitney). Conclusion : Anemia in patients with CHF represents a significant factor of a bad prognosis and can cause more frequent hospitalizations and examinations in the emergency department. Even treating these patients with high doses of oral iron hasn’t led to a clinical improvement, so a new protocol was introduced with a proven and beneficial treatment of these patients with high dose intravenous iron.

    Cardiologia Croatica
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    The influence of anemia on repeated hospitalization in patients with heart failure and left ventricular systolic disfunction

    Extended Abstract
    Issue11-12
    Published
    Pages354
    PDF via DOIhttps://doi.org/10.15836/ccar2018.354
    anemia
    iron deficiency
    heart failure
    hospitalization

    Authors

    Ivo Darko Gabrić*ORCIDUniversity Hospital Centre „Sestre milosrdnice”, Zagreb, Croatia
    Ivana TomašićORCIDUniversity Hospital Centre „Sestre milosrdnice”, Zagreb, Croatia
    Karlo GolubićORCIDUniversity Hospital Centre „Sestre milosrdnice”, Zagreb, Croatia
    Matias TrbušićORCIDUniversity Hospital Centre „Sestre milosrdnice”, Zagreb, Croatia
    Jasna Čerkez HabekORCIDUniversity Hospital Centre „Sestre milosrdnice”, Zagreb, Croatia
    Diana Delić-BrkljačićORCIDUniversity Hospital Centre „Sestre milosrdnice”, Zagreb, Croatia

    Full Text

    Zaključak: Anemija u bolesnika s KZS predstavlja značajni faktor loše prognoze te može uzrokovati učestalije hospitalizacije i preglede u hitnoj ambulanti. Kako liječenje čak i visokim dozama peroralnog željeza kod tih bolesnika nije dovelo do kliničkog poboljšanja uveden je novi protokol dokazano korisnog liječenja tih bolesnika visokodoznim intravenskim željezom. Introduction: Anemia is frequent in patients with chronic heart failure (CHF) and is connected to a worse prognosis, regardless the severity and type. The correction of anemia contributes to the improvement of health, which also reduces the number of hospitalizations, improves the survival rate and the quality of life. ( 1 - 3 ) Patients and Methods: This retrospective analysis includes patients with CHF and a reduced systolic function of the left ventricle who have been treated for the last three years at the Department of Cardiology University Hospital Centre “Sestre milosrdnice“ in Zagreb. The method of parallel sample was used to compare the data of a hundred patients with anemia and a hundred patients without anemia. Using the statistical analysis of multiple factors it was attempted to determine the influence of anemia as an independent risk factor in the number of repeated hospitalizations. Results: Although patients with anemia were older than those without anemia (median 77 (66-85): 67.5 (58-75.3); p <0.0001, Mann-Whitney), it was determined that patients with CHF and anemia were hospitalized more frequently than those who have CHF without anemia (median 4 (3-6):2 (1-4); p <0.0001, Mann-Whitney). Patients with anemia were more often examined in the unified urgent reception (median (4 (3-6): 2 (1-4); p <0.0001, Mann-Whitney). Conclusion : Anemia in patients with CHF represents a significant factor of a bad prognosis and can cause more frequent hospitalizations and examinations in the emergency department. Even treating these patients with high doses of oral iron hasn’t led to a clinical improvement, so a new protocol was introduced with a proven and beneficial treatment of these patients with high dose intravenous iron.