Secondary mitral regurgitation according to gender

    Authors

    Keywords

    secondary mitral regurgitation, gender

    DOI

    https://doi.org/10.15836/ccar2018.184

    Full Text

    Background : Mitral regurgitation (MR) represents the second most common valvular heart disease (VHD) ( 1 ). It is classified as primary (organic) and secondary (functional) MR, with secondary being more frequent ( 2 ). Secondary MR is usually result of dilatative cardiomyopathy, ischemic heart disease, postmyocarditis and similar ( 2 ). Its prevalence is approximately 1.6% to 19.4%, and is associated with worse prognosis than primary ( 3 ). The aim of our study was to investigate the incidence of secondary MR according to gender. Patients and Methods : Retrospective study was conducted to assess the relation between MR with other VHD. A total of 686 patients, with male predominance of 55%, were included in the study. Results : Among all patients with MR 167 (24.3%) had secondary MR. The main cause was left ventricular enlargement with mitral annular dilatation, counting for 96 (57.5% of secondary MR patients and 14.0% of all MR patients). Other causes of secondary MR included ischemic and postmyocarditis causes, with frequency of 64 (38.3% of secondary MR patients and 9.3% of all MR patients) and 7 (4% of secondary MR patients and 1% of all MR patients), respectively. According to gender distribution, 99 (59.3%) males and 68 (40.7%) females had secondary MR. Dilatative cardiomyopathy was the main cause of secondary MR in both men and women (60.6% and 52.9%). Ischemic MR was present in 36 (36.4%) men, 28 (41%) women, while postmyocarditis MR was observed in 3 (3%) of men and 4(5.8%). Conclusion : Secondary MR presents high proportion of all MR causes. Dilatative cardiomyopathy was most common cause of secondary MR, regardless of gender groups, with men more affected. Ischemic cause was slightly more common in women than men.

    Cardiologia Croatica
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    Secondary mitral regurgitation according to gender

    Extended Abstract
    Issue5-6
    Published
    Pages184
    PDF via DOIhttps://doi.org/10.15836/ccar2018.184
    secondary mitral regurgitation
    gender

    Authors

    Marko Perčić*ORCIDUniversity Hospital “Sveti Duh”, Zagreb, Croatia
    Zrinka PlaninićORCIDUniversity Hospital “Sveti Duh”, Zagreb, Croatia
    Ante PašalićORCIDUniversity Hospital “Sveti Duh”, Zagreb, Croatia
    Tea FriščićORCIDUniversity Hospital “Sveti Duh”, Zagreb, Croatia
    Dario GulinORCIDUniversity Hospital “Sveti Duh”, Zagreb, Croatia
    Leon AdrovićORCIDUniversity Hospital “Sveti Duh”, Zagreb, Croatia
    Dijana BešićORCIDUniversity Hospital “Sveti Duh”, Zagreb, Croatia
    Jozica ŠikićORCIDUniversity Hospital “Sveti Duh”, Zagreb, Croatia

    Full Text

    Background : Mitral regurgitation (MR) represents the second most common valvular heart disease (VHD) ( 1 ). It is classified as primary (organic) and secondary (functional) MR, with secondary being more frequent ( 2 ). Secondary MR is usually result of dilatative cardiomyopathy, ischemic heart disease, postmyocarditis and similar ( 2 ). Its prevalence is approximately 1.6% to 19.4%, and is associated with worse prognosis than primary ( 3 ). The aim of our study was to investigate the incidence of secondary MR according to gender. Patients and Methods : Retrospective study was conducted to assess the relation between MR with other VHD. A total of 686 patients, with male predominance of 55%, were included in the study. Results : Among all patients with MR 167 (24.3%) had secondary MR. The main cause was left ventricular enlargement with mitral annular dilatation, counting for 96 (57.5% of secondary MR patients and 14.0% of all MR patients). Other causes of secondary MR included ischemic and postmyocarditis causes, with frequency of 64 (38.3% of secondary MR patients and 9.3% of all MR patients) and 7 (4% of secondary MR patients and 1% of all MR patients), respectively. According to gender distribution, 99 (59.3%) males and 68 (40.7%) females had secondary MR. Dilatative cardiomyopathy was the main cause of secondary MR in both men and women (60.6% and 52.9%). Ischemic MR was present in 36 (36.4%) men, 28 (41%) women, while postmyocarditis MR was observed in 3 (3%) of men and 4(5.8%). Conclusion : Secondary MR presents high proportion of all MR causes. Dilatative cardiomyopathy was most common cause of secondary MR, regardless of gender groups, with men more affected. Ischemic cause was slightly more common in women than men.