Relationship between anthropometric and cardiometabolic parameters in adipose patients

    Authors

    Abstract

    The aim of the study was to determine the correlation between the parameters of obesity (waist circumference, hips, waist/hip ratio) and body mass index (BMI) in 48 patients, 15 male and 33 female, and laboratory findings (lipidogram, glucose, insulin, HOMA (homeostatic model assessment) index) with echocardiographic findings (LViDd, LViDs, left atrium (LA) area, LA volume, E/E’) which values are most correlated with body weight gain. Bayesian Pearson correlation was used in the study to determine the degree of positive correlation (significant coefficient value 0.5 and above). Statistical analysis and correlation of all parameters according to sex, to the subgroup of patients with diabetes and hypertension, or group without comorbidity was performed. Average values: waist circumference 126.6 cm (92.9-180.0), waist circumference 134.3 cm (108-174), waist circumference and hips 0.93 (0.74-1.16), BMI 43.17 kg/m2 (28.91-63.67), insulin 20.35 pmol/L (4.5-88.2), HOMA index 5.02 (0.9- 21.95) for niacytes, of which 15 (35%) patients did not have insulin resistance. Most had a normal left ventricular ejection fraction (on average EF LV 65%). We analyzed correlations of anthropometric and laboratory findings with echocardiographic parameters and showed significantly correlated correlations. Positive significant correlation was found: LViDd and BMI (r = 0.52, BF10 is 121), LViDs and BMI (r = 0.50, BF10 = 65), LViDd and waist circumference (r = 0.56, BF10 = 150) waist circumference (r = 0.55, BF10 = 106), a stronger degree of attachment for men than female gender (R = 0.67, BF10 = 5.23), LViDs and waist circumference (r = 0.61, BF10 = 0.64, BF10 = 4.28). (R = 0.37, BF10 = 1.71), LViDd and waist circumference (r = 0.28, BF10 = 0.59), LViDs and waist circumference (r = 0.37, BF10 = 1.61), LViDs and BMI 0.18, BF10 = 0.36). Findings for diabetic and hypertensive patients: LViDd 5.55 cm (4.54-7.49), LA 3.47cm (2.88-5.96), LA area 18.30 (12.0- 25.6) cm2, LA volume 47.83ml (25.0-76.0), E/E’ 9.83 (6.0 -13), LA volume 48.82 (23.0-99.0), E/E’ averaged 9, 4.2, 41 (6.0-15.0). Adipose men with diabetes and hypertension have significantly more pronounced echocardiographic changes compared to adipose patients without comorbidity. (1-3)

    Keywords

    antropometric parameters, obesity, cardiometabolic parameters

    DOI

    https://doi.org/10.15836/ccar2018.386

    Literature

    1. Kosmala W, Wong C, Kuliczkowska J, Leano R, Przewlocka-Kosmala M, Marwick TH. Use of body weight and insulin resistance to select obese patients for echocardiographic assessment of subclinical left ventricular dysfunction. Am J Cardiol. 2008 May 1;101(9):1334–40. https://doi.org/10.1016/j.amjcard.2007.12.034
    2. Crea P, Zito C, Cusmà Piccione M, Arcidiaco S, Todaro MC, Oreto L, et al. The role of echocardiography in the evaluation of cardiac damage in hypertensive obese patient. High Blood Press Cardiovasc Prev. 2015 Mar;22(1):23–7. https://doi.org/10.1007/s40292-014-0058-z
    3. De Jong KA, Czeczor JK, Sithara S, McEwen K, McEwen K, Lopaschuk GD, et al. Obesity and type 2 diabetes have additive effects on left ventricular remodelling in normotensive patients-a cross sectional study. Cardiovasc Diabetol. 2017 Feb 8;16(1):21. https://doi.org/10.1186/s12933-017-0504-z
    Cardiologia Croatica
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    Relationship between anthropometric and cardiometabolic parameters in adipose patients

    Abstract
    Issue11-12
    Published
    Pages386
    PDF via DOIhttps://doi.org/10.15836/ccar2018.386
    antropometric parameters
    obesity
    cardiometabolic parameters

    Authors

    Martina MatovinovićORCIDMedicinski fakultet Sveučilišta u Zagrebu, Klinički bolnički centar Zagreb, Zagreb, Hrvatska
    Kristina GašparovićORCIDMedicinski fakultet Sveučilišta u Zagrebu, Klinički bolnički centar Zagreb, Zagreb, Hrvatska
    Dubravka MemićORCIDMedicinski fakultet Sveučilišta u Zagrebu, Klinički bolnički centar Zagreb, Zagreb, Hrvatska
    Lada BradićORCIDMedicinski fakultet Sveučilišta u Zagrebu, Klinički bolnički centar Zagreb, Zagreb, Hrvatska
    Rea LevickiORCIDOpća županijska bolnica Požega, Požega, Hrvatska
    Ivana Vukovac ŠokecORCIDOpća bolnica “Dr.Tomislav Bardek”, Koprivnica, Hrvatska
    Martina Lovrić Benčić*ORCIDMedicinski fakultet Sveučilišta u Zagrebu, Klinički bolnički centar Zagreb, Zagreb, Hrvatska

    *Correspondence email: mlbencic@icloud.com

    Abstract

    The aim of the study was to determine the correlation between the parameters of obesity (waist circumference, hips, waist/hip ratio) and body mass index (BMI) in 48 patients, 15 male and 33 female, and laboratory findings (lipidogram, glucose, insulin, HOMA (homeostatic model assessment) index) with echocardiographic findings (LViDd, LViDs, left atrium (LA) area, LA volume, E/E’) which values are most correlated with body weight gain. Bayesian Pearson correlation was used in the study to determine the degree of positive correlation (significant coefficient value 0.5 and above). Statistical analysis and correlation of all parameters according to sex, to the subgroup of patients with diabetes and hypertension, or group without comorbidity was performed. Average values: waist circumference 126.6 cm (92.9-180.0), waist circumference 134.3 cm (108-174), waist circumference and hips 0.93 (0.74-1.16), BMI 43.17 kg/m2 (28.91-63.67), insulin 20.35 pmol/L (4.5-88.2), HOMA index 5.02 (0.9- 21.95) for niacytes, of which 15 (35%) patients did not have insulin resistance. Most had a normal left ventricular ejection fraction (on average EF LV 65%). We analyzed correlations of anthropometric and laboratory findings with echocardiographic parameters and showed significantly correlated correlations. Positive significant correlation was found: LViDd and BMI (r = 0.52, BF10 is 121), LViDs and BMI (r = 0.50, BF10 = 65), LViDd and waist circumference (r = 0.56, BF10 = 150) waist circumference (r = 0.55, BF10 = 106), a stronger degree of attachment for men than female gender (R = 0.67, BF10 = 5.23), LViDs and waist circumference (r = 0.61, BF10 = 0.64, BF10 = 4.28). (R = 0.37, BF10 = 1.71), LViDd and waist circumference (r = 0.28, BF10 = 0.59), LViDs and waist circumference (r = 0.37, BF10 = 1.61), LViDs and BMI 0.18, BF10 = 0.36). Findings for diabetic and hypertensive patients: LViDd 5.55 cm (4.54-7.49), LA 3.47cm (2.88-5.96), LA area 18.30 (12.0- 25.6) cm2, LA volume 47.83ml (25.0-76.0), E/E’ 9.83 (6.0 -13), LA volume 48.82 (23.0-99.0), E/E’ averaged 9, 4.2, 41 (6.0-15.0). Adipose men with diabetes and hypertension have significantly more pronounced echocardiographic changes compared to adipose patients without comorbidity. (1-3)

    Literature

    1. 1.
      Kosmala W, Wong C, Kuliczkowska J, Leano R, Przewlocka-Kosmala M, Marwick TH. Use of body weight and insulin resistance to select obese patients for echocardiographic assessment of subclinical left ventricular dysfunction. Am J Cardiol. 2008 May 1;101(9):1334–40.DOI
    2. 2.
      Crea P, Zito C, Cusmà Piccione M, Arcidiaco S, Todaro MC, Oreto L, et al. The role of echocardiography in the evaluation of cardiac damage in hypertensive obese patient. High Blood Press Cardiovasc Prev. 2015 Mar;22(1):23–7.DOI
    3. 3.
      De Jong KA, Czeczor JK, Sithara S, McEwen K, McEwen K, Lopaschuk GD, et al. Obesity and type 2 diabetes have additive effects on left ventricular remodelling in normotensive patients-a cross sectional study. Cardiovasc Diabetol. 2017 Feb 8;16(1):21.DOI