Authors
- Martina Matovinović — University Hospital Centre Zagreb, Zagreb, Croatia — ORCID: 0000-0002-6325-7394
- Kristina Gašparović — University Hospital Centre Zagreb, Zagreb, Croatia — ORCID: 0000-0002-1191-4831
- Dubravka Memić — University Hospital Centre Zagreb, Zagreb, Croatia — ORCID: 0000-0003-0398-4618
- Lada Bradić — University Hospital Centre Zagreb, Zagreb, Croatia — ORCID: 0000-0001-8296-699X
- Rea Levicki — University Hospital Centre Zagreb, Zagreb, Croatia — ORCID: 0000-0003-3687-1310
- Ivana Vukovac Šokec — University Hospital Centre Zagreb, Zagreb, Croatia — ORCID: 0000-0002-5405-7673
- Martina Lovrić Benčić — University Hospital Centre Zagreb, Zagreb, Croatia — ORCID: 0000-0001-8446-6120
Keywords
antropometric parameters, obesity, cardiometabolic parameters
DOI
https://doi.org/10.15836/ccar2018.386Full Text
The aim of the study was to determine the correlation between the parameters of obesity (waist circumference, hips, waist/hip ratio) and body mass index (BMI) in 48 patients, 15 male and 33 female, and laboratory findings (lipidogram, glucose, insulin, HOMA (homeostatic model assessment) index) with echocardiographic findings (LViDd, LViDs, left atrium (LA) area, LA volume, E/E’) which values are most correlated with body weight gain. Bayesian Pearson correlation was used in the study to determine the degree of positive correlation (significant coefficient value 0.5 and above). Statistical analysis and correlation of all parameters according to sex, to the subgroup of patients with diabetes and hypertension, or group without comorbidity was performed. Average values: waist circumference 126.6 cm (92.9-180.0), waist circumference 134.3 cm (108-174), waist circumference and hips 0.93 (0.74-1.16), BMI 43.17 kg/m 2 (28.91-63.67), insulin 20.35 pmol/L (4.5-88.2), HOMA index 5.02 (0.9- 21.95) for niacytes, of which 15 (35%) patients did not have insulin resistance. Most had a normal left ventricular ejection fraction (on average EF LV 65%). We analyzed correlations of anthropometric and laboratory findings with echocardiographic parameters and showed significantly correlated correlations. Positive significant correlation was found: LViDd and BMI (r = 0.52, BF10 is 121), LViDs and BMI (r = 0.50, BF10 = 65), LViDd and waist circumference (r = 0.56, BF10 = 150) waist circumference (r = 0.55, BF10 = 106), a stronger degree of attachment for men than female gender (R = 0.67, BF10 = 5.23), LViDs and waist circumference (r = 0.61, BF10 = 0.64, BF10 = 4.28). (R = 0.37, BF10 = 1.71), LViDd and waist circumference (r = 0.28, BF10 = 0.59), LViDs and waist circumference (r = 0.37, BF10 = 1.61), LViDs and BMI 0.18, BF10 = 0.36). Findings for diabetic and hypertensive patients: LViDd 5.55 cm (4.54-7.49), LA 3.47cm (2.88-5.96), LA area 18.30 (12.0- 25.6) cm 2 , LA volume 47.83ml (25.0-76.0), E/E’ 9.83 (6.0 -13), LA volume 48.82 (23.0-99.0), E/E’ averaged 9, 4.2, 41 (6.0-15.0). Adipose men with diabetes and hypertension have significantly more pronounced echocardiographic changes compared to adipose patients without comorbidity. ( 1 - 3 )