Primary mitral regurgitation according to gender

    Authors

    Abstract

    **Introduction:** Mitral regurgitation (MR) represents the second most common valvular heart disease (1). It is classified as primary (organic) and secondary (functional) MR, with secondary being more frequent (2). Degenerative valvular disease, rheumatic fever, infective endocarditis and mitral valve prolapse are most common causes of primary MR**2**. On the other hand, secondary MR is usually result of ischemic heart disease or dilatative cardiomyopathy (2). The aim of our study was to investigate the incidence of primary MR according to gender. **Patients and Methods:** Retrospective study was conducted to assess the relation between MR with other VHD. A total of 686 patients, with male predominance of 55%, were included in the study. **Results:** Among all patients with MR 519 (75.6%) had primary MR. Degenerative valvular heart disease was the main cause of primary MR, counting for 474 patients (91.3%). Other causes of primary MR included mitral valve prolapse, rheumatic valvular heart disease, and other causes, with frequency of 19 (3.6%), 5 (1%), 21 (4.1%), respectively. According to gender distribution, 290 (55.9%) males and 229 (44.1%) females had primary MR. Degenerative mitral valve disease was the main cause of primary MR in both men and women (90.3 and 92.5%), while the least frequent was infective endocarditis among men and rheumatic heart disease among women. **Conclusion:** Degenerative MR was most common cause of primary MR. Regardless of gender groups, with women slightly more affected.

    Keywords

    mitral regurgitation, primary, gender

    DOI

    https://doi.org/10.15836/ccar2018.183

    Literature

    1. Andell P, Li X, Martinsson A, Andersson C, Stagmo M, Zöller B, et al. Epidemiology of valvular heart disease in a Swedish nationwide hospital-based register study. Heart. 2017 Nov;103(21):1696–703. https://doi.org/10.1136/heartjnl-2016-310894
    2. Okura H, Kataoka T, Yoshida K. Renin-angiotensin system inhibitors in patients with myocardial infarction and secondary mitral regurgitation. Heart. 2016 May;102(9):694–700. https://doi.org/10.1136/heartjnl-2015-308536
    Cardiologia Croatica
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    Primary mitral regurgitation according to gender

    Extended Abstract
    Issue5-6
    Published
    Pages183
    PDF via DOIhttps://doi.org/10.15836/ccar2018.183
    mitral regurgitation
    primary
    gender

    Authors

    Dario Gulin*ORCIDUniversity Hospital “Sveti Duh”, Zagreb, Croatia
    Ante PašalićORCIDUniversity Hospital “Sveti Duh”, Zagreb, Croatia
    Zrinka PlaninićORCIDUniversity Hospital “Sveti Duh”, Zagreb, Croatia
    Marko PerčićORCIDUniversity Hospital “Sveti Duh”, Zagreb, Croatia
    Tea FriščićORCIDUniversity Hospital “Sveti Duh”, Zagreb, Croatia
    Leon AdrovićORCIDUniversity Hospital “Sveti Duh”, Zagreb, Croatia
    Dijana BešićORCIDUniversity Hospital “Sveti Duh”, Zagreb, Croatia
    Jozica ŠikićORCIDUniversity Hospital “Sveti Duh”, Zagreb, Croatia

    *Correspondence email: dariogulin@gmail.com

    Abstract

    **Introduction:** Mitral regurgitation (MR) represents the second most common valvular heart disease (1). It is classified as primary (organic) and secondary (functional) MR, with secondary being more frequent (2). Degenerative valvular disease, rheumatic fever, infective endocarditis and mitral valve prolapse are most common causes of primary MR**2**. On the other hand, secondary MR is usually result of ischemic heart disease or dilatative cardiomyopathy (2). The aim of our study was to investigate the incidence of primary MR according to gender. **Patients and Methods:** Retrospective study was conducted to assess the relation between MR with other VHD. A total of 686 patients, with male predominance of 55%, were included in the study. **Results:** Among all patients with MR 519 (75.6%) had primary MR. Degenerative valvular heart disease was the main cause of primary MR, counting for 474 patients (91.3%). Other causes of primary MR included mitral valve prolapse, rheumatic valvular heart disease, and other causes, with frequency of 19 (3.6%), 5 (1%), 21 (4.1%), respectively. According to gender distribution, 290 (55.9%) males and 229 (44.1%) females had primary MR. Degenerative mitral valve disease was the main cause of primary MR in both men and women (90.3 and 92.5%), while the least frequent was infective endocarditis among men and rheumatic heart disease among women. **Conclusion:** Degenerative MR was most common cause of primary MR. Regardless of gender groups, with women slightly more affected.

    Literature

    1. 1.
      Andell P, Li X, Martinsson A, Andersson C, Stagmo M, Zöller B, et al. Epidemiology of valvular heart disease in a Swedish nationwide hospital-based register study. Heart. 2017 Nov;103(21):1696–703.DOI
    2. 2.
      Okura H, Kataoka T, Yoshida K. Renin-angiotensin system inhibitors in patients with myocardial infarction and secondary mitral regurgitation. Heart. 2016 May;102(9):694–700.DOI