Polyvascular atherosclerotic disease and multiple risk factors: focus on arterial hypertension

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    Keywords

    polyvascular atherosclerotic disease, arterial hypertension, multiple risk factors

    DOI

    https://doi.org/10.15836/ccar.2015.238

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    Introduction: The goal of this study is to evaluate the role of arterial hypertension (HTA) in patients (pts) with atherosclerotic disease (AthD) of coronary arteries (CAD), carotid arteries (CdA) and iliaco-femoro-popliteal (IFP) arteries. ( 1 - 3 ) Patients and Methods: The study included a total of 311 pts with with clear clinical AthD. We evaluated the presence of CAD, CdA, and IFP as well as clinical variables: age, gender, arterial hypertension (HTA), tobacco, hyperlipidemia (HLP), obesity (BMI), fibrinogen and diabetes mellitus. The risk factors score was calculated as x/8. Special focus was given to pts with HTA (n=183) who were divided in two subgroups; isolated systolic HTA and systolic/diastolic HTA. Results: The study included a total of 311 pts, 207 males and 104 females, average age of 64 ±11.2 years. Combination of IFP + CAD was registered in 124 pts, with multiple risk factors (MRF) score 4.35, IFP+CdA was registered in 78 pts, with MRF score 4.51, and IFP+CAD+CdA in 109 pts, with MRF score 4.59. HTA was present in 132 pts (42.4%, p<0.01), 86 males and 48 females, with the average age 67.8±12.9. Isolated systolic HTA was registered in 84 pts (63.6%), and systolic/diastolic HTA in 48 pts (36.4%). There was a significant relation between the IFP+CAD pts and isolated systolic HTA, r=.81, p<0.001 and borderline significant relation between IFP+CAD+CdA pts and systolic/diastolic HTA, r=42, p=0.07. Conclusions: (1) We found a clear link between the PolyAthD and elevated MRF score (r=.64, p<0.01), especially clinical variables HTA (p<0.01) and tobacco (p<0.01). (2) We established a borderline relation rank between dual disease (IFP+CAD and IFP+CdA) and MRF score (r=.46, p<0.05), (3) There was a statistically significant relation between IFP+CAD patients and isolated systolic HTA, r=.81, p<0.001, and a non-significant relation between IFP+CAD and IFP+CAD+CdA disease and systolic/diastolic HTA, r=36, p=0.9.

    Cardiologia Croatica
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    Polyvascular atherosclerotic disease and multiple risk factors: focus on arterial hypertension

    Abstract
    Issue9-10
    Published
    Pages238
    PDF via DOIhttps://doi.org/10.15836/ccar.2015.238
    polyvascular atherosclerotic disease
    arterial hypertension
    multiple risk factors

    Authors

    Alden Begic*ORCID
    Amina BicoORCID
    Lana LekicORCID
    Admir Tanovic
    Demir BejtovicORCID
    Mehmed KulicORCID
    Mirza DilicORCID

    Full Text

    Introduction: The goal of this study is to evaluate the role of arterial hypertension (HTA) in patients (pts) with atherosclerotic disease (AthD) of coronary arteries (CAD), carotid arteries (CdA) and iliaco-femoro-popliteal (IFP) arteries. ( 1 - 3 ) Patients and Methods: The study included a total of 311 pts with with clear clinical AthD. We evaluated the presence of CAD, CdA, and IFP as well as clinical variables: age, gender, arterial hypertension (HTA), tobacco, hyperlipidemia (HLP), obesity (BMI), fibrinogen and diabetes mellitus. The risk factors score was calculated as x/8. Special focus was given to pts with HTA (n=183) who were divided in two subgroups; isolated systolic HTA and systolic/diastolic HTA. Results: The study included a total of 311 pts, 207 males and 104 females, average age of 64 ±11.2 years. Combination of IFP + CAD was registered in 124 pts, with multiple risk factors (MRF) score 4.35, IFP+CdA was registered in 78 pts, with MRF score 4.51, and IFP+CAD+CdA in 109 pts, with MRF score 4.59. HTA was present in 132 pts (42.4%, p<0.01), 86 males and 48 females, with the average age 67.8±12.9. Isolated systolic HTA was registered in 84 pts (63.6%), and systolic/diastolic HTA in 48 pts (36.4%). There was a significant relation between the IFP+CAD pts and isolated systolic HTA, r=.81, p<0.001 and borderline significant relation between IFP+CAD+CdA pts and systolic/diastolic HTA, r=42, p=0.07. Conclusions: (1) We found a clear link between the PolyAthD and elevated MRF score (r=.64, p<0.01), especially clinical variables HTA (p<0.01) and tobacco (p<0.01). (2) We established a borderline relation rank between dual disease (IFP+CAD and IFP+CdA) and MRF score (r=.46, p<0.05), (3) There was a statistically significant relation between IFP+CAD patients and isolated systolic HTA, r=.81, p<0.001, and a non-significant relation between IFP+CAD and IFP+CAD+CdA disease and systolic/diastolic HTA, r=36, p=0.9.