Influence of body mass index on survival and length of hospital stay in heart transplantation versus left ventricular assist device recipients

    Authors

    Keywords

    body mass index, heart transplantation, left ventricular assist device

    DOI

    https://doi.org/10.15836/ccar.2015.210

    Full Text

    Purpose: There is a substantial amount of data demonstrating the influence of body mass index (BMI) on outcomes of patients after heart transplantation (HTx) or left ventricular assist device (LVAD) implantation. However, no direct comparisons were made between these two modalities of advanced heart failure treatment in a specific population in terms of pretreatment BMI. ( 1 - 3 ) Patients and Methods: We retrospectively studied 90 consecutive HTx (67 male, mean age 51.9±13, median follow-up 20.8 months) and 32 consecutive LVAD (27 male, mean age 58.3±8, mean follow-up 13.1 months) patients from our centre in the period from January 2010 to December 2014. The patients were categorized in groups according to pretreatment BMI: non-overweight patients (BMI <25) and overweight/obese patients (BMI ≥25). Survival and post-surgical length-of-hospital stay were compared among the groups by Kaplan-Meier method (log-rank test for comparison). Results: Pre-treatment BMI distribution among groups is shown in Table 1 . HTx patients in the non-overweight group had significantly better survival in comparison to LVAD patients in the same BMI group. This observation was not present in patients with BMI ≥25, where survival post Htx and post LVAD were similar ( Figure 1 ). There was no significant overall difference in length of hospital stay between the groups ( Figure 2 ). Kaplan-Meier survival curves for body mass index groups in relation to different treatment options. Modified Kaplan-Meier curves representing length of hospital stay for body mass index groups in relation to different treatment options. Conclusion: Non-overweight patients in our cohort demonstrated better survival with HTx than LVAD treatment. No influence of BMI on length of hospital stay was shown between the HTx and LVAD treatment groups.

    Cardiologia Croatica
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    Influence of body mass index on survival and length of hospital stay in heart transplantation versus left ventricular assist device recipients

    Abstract
    Issue9-10
    Published
    Pages210-211
    PDF via DOIhttps://doi.org/10.15836/ccar.2015.210
    body mass index
    heart transplantation
    left ventricular assist device

    Authors

    Ivo Planinc*ORCIDCroatia
    Dora FabijanovicORCIDCroatia
    Boško SkoricORCIDCroatia
    Jana Ljubas MacekORCIDCroatia
    Hrvoje JurinORCIDCroatia
    Jure SamardzicORCIDCroatia
    Zeljko BaricevicORCIDCroatia
    Hrvoje GašparovicORCIDCroatia
    Maja CikešORCIDCroatia
    Davor MilicicORCIDCroatia

    Full Text

    Purpose: There is a substantial amount of data demonstrating the influence of body mass index (BMI) on outcomes of patients after heart transplantation (HTx) or left ventricular assist device (LVAD) implantation. However, no direct comparisons were made between these two modalities of advanced heart failure treatment in a specific population in terms of pretreatment BMI. ( 1 - 3 ) Patients and Methods: We retrospectively studied 90 consecutive HTx (67 male, mean age 51.9±13, median follow-up 20.8 months) and 32 consecutive LVAD (27 male, mean age 58.3±8, mean follow-up 13.1 months) patients from our centre in the period from January 2010 to December 2014. The patients were categorized in groups according to pretreatment BMI: non-overweight patients (BMI <25) and overweight/obese patients (BMI ≥25). Survival and post-surgical length-of-hospital stay were compared among the groups by Kaplan-Meier method (log-rank test for comparison). Results: Pre-treatment BMI distribution among groups is shown in Table 1 . HTx patients in the non-overweight group had significantly better survival in comparison to LVAD patients in the same BMI group. This observation was not present in patients with BMI ≥25, where survival post Htx and post LVAD were similar ( Figure 1 ). There was no significant overall difference in length of hospital stay between the groups ( Figure 2 ). Kaplan-Meier survival curves for body mass index groups in relation to different treatment options. Modified Kaplan-Meier curves representing length of hospital stay for body mass index groups in relation to different treatment options. Conclusion: Non-overweight patients in our cohort demonstrated better survival with HTx than LVAD treatment. No influence of BMI on length of hospital stay was shown between the HTx and LVAD treatment groups.