Authors

• Josip Vincelj — University Hospital Dubrava, Zagreb, Croatia — ORCID: 0000-0003-0064-9128
• Sandra Jakšić Jurinjak — University Hospital Dubrava, Zagreb, Croatia — ORCID: 0000-0002-7349-6137
• Mario Udovičić — University Hospital Dubrava, Zagreb, Croatia — ORCID: 0000-0001-9912-2179
• Kristina Milevoj Križić — Bjelovar General Hospital, Bjelovar, Croatia
• Ante Lisičić — University Hospital Dubrava, Zagreb, Croatia — ORCID: 0000-0002-4365-9652
• Mira Stipčević — University Hospital Dubrava, Zagreb, Croatia — ORCID: 0000-0003-4351-1102

Keywords

body mass index, coronary artery bypass surgery, major adverse cardiac events

DOI

Full Text

**Introduction:** The main goal of the coronary artery bypass graft (CABG) surgery is to reduce the mortality and to reduce or to prevent symptoms of coronary artery disease. Five years after coronary bypass graft surgery 75% of patients didn’t have ischemic events (1, 2). Obesity is the risk factor for morbidity and mortality after coronary artery bypass graft surgery (3). The main goal of the research is to asses relative impact of body mass index (BMI) on major adverse cardiac events (MACE) after CABG in the long term follow up. **Patients and Methods:** In study are involved 100 consecutive patients after CABG surgery at the age of 36-79, average 61.3. Follow up time is about 2 to 29 years, average 8.6 years. BMI is calculated from the formula; body weight (kg) / body height (m2). Based on BMI the patients are divided in two groups; 1. Group with BMI 2; 2. Group with BMI ≥25 kg/m2. MACE include mortality due to cardiac cause, myocardial infarction, unstable angina pectoris, repeated myocardial revascularization, congestive heart failure, stoke, transient ischemic attack (TIA) and death due to all other causes. **Results:** Frequency of arterial hypertension, diabetes, dyslipidemia is higher in a group of patients with excessive weight (82.9%, 34.1%, 87.5%), than in patients with normal weight (75%, 25%, 75%). The majority of smokers are in the group with normal body mass index (51.5%) then in group with excess body mass index (51.5%). During the follow up; 12 patients died (7 of them due to cardiac cause and 5 due to other cause of death), acute myocardial infarction had 11 patients. Of all the 23 patients, only two of them had BMI less than 25kg/m2. Repeated cardiac revascularization had been done in 12 patients, and 7 patients had stroke or TIA. Due to unstable angina pectoris 12 patients were treated, and 8 patients were treated from heart failure. Death due to all other causes during the follow up was in 12% of patients. **Conclusion:** The results of the research show greater frequency of classic risk factors of coronary artery disease in group of patients with higher BMI. Body mass index greater than 25 kg/m2 can be predictor of the MACE after the CABG surgery in the long term follow-up.

Literature

1. Vincelj J, Bitar L, Jendričko T, Udovičić M, Petrovečki M. Health-related quality of life five years after coronary artery bypass graft surgery. Int J Cardiol. 2015;182:68–9. https://doi.org/10.1016/j.ijcard.2014.12.106
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3. Wang ZJ, Zhou YJ, Zhao YX, Liu YY, Shi DM, Liu XL, et al. Effect of obesity on repeat revascularization in patients undergoing percutaneous coronary intervention with drug-eluting stents. Obesity (Silver Spring). 2012;20(1):141–6. https://doi.org/10.1038/oby.2011.187