Authors

• Duška Glavaš — University Hospital Centre Split, Split, Croatia — ORCID: 0000-0003-2649-0936
• Lovre Bojić — University Hospital Centre Split, Split, Croatia — ORCID: 0000-0001-5649-0756
• Ratko Ermacora — University Hospital Centre Split, Split, Croatia — ORCID: 0000-0002-7049-5454
• Bruna Bojić — University Hospital Centre Split, Split, Croatia — ORCID: 0000-0002-5410-8610

Abstract

**Introduction**: Cardiovascular illness are more often observed in glaucoma patients. (1) The purpose of the study was to assess the ultrasound measurements of the brachial artery flow-mediated dilation (FMD) in patients with glaucoma. **Patients and Methods**: Thirty-seven patients with glaucoma and thirty-one healthy controls were included in the study. All glaucoma patients and controls underwent ultrasound measurement of FMD of the brachial artery. **Results**: The mean values of brachial FMD were significantly lower among glaucoma group compared with control group (15.3 ± 9.5% vs 19.8 ± 9.3%; p=0.04). No significant difference was found in brachial artery diameter at rest (4.7 ± 0.6 vs. 4.9 ± 0.3; p=0.2) between glaucoma patients and controls. The significant difference in brachial artery diameter in hyperemia between patients with glaucoma and control group (5.4 ± 0.6 vs. 5.9 ± 0.4; p=0.002) was detected. A negative correlation among brachial FMD and brachial artery diameter at rest was found. **Conclusion**: Impaired brachial FMD could indicate presence of systemic vascular endothelial dysfunction in patients with glaucoma.

Keywords

endothelial function, flow-mediated dilation, glaucoma

DOI

Literature

1. Bojić L, Ermacora R, Polić S, Ivanisević M, Mandić Z, Rogosić V, et al. Pseudoexfoliation syndrome and asymptomatic myocardial dysfunction. Graefes Arch Clin Exp Ophthalmol. 2005 May;243(5):446–9. https://doi.org/10.1007/s00417-004-1074-9