Endothelial function in patients with glaucoma

    Authors

    Keywords

    endothelial function, flow-mediated dilation, glaucoma

    DOI

    https://doi.org/10.15836/ccar2017.380

    Full Text

    Introduction : Cardiovascular illness are more often observed in glaucoma patients. ( 1 ) The purpose of the study was to assess the ultrasound measurements of the brachial artery flow-mediated dilation (FMD) in patients with glaucoma. Patients and Methods : Thirty-seven patients with glaucoma and thirty-one healthy controls were included in the study. All glaucoma patients and controls underwent ultrasound measurement of FMD of the brachial artery. Results : The mean values of brachial FMD were significantly lower among glaucoma group compared with control group (15.3 ± 9.5% vs 19.8 ± 9.3%; p=0.04). No significant difference was found in brachial artery diameter at rest (4.7 ± 0.6 vs. 4.9 ± 0.3; p=0.2) between glaucoma patients and controls. The significant difference in brachial artery diameter in hyperemia between patients with glaucoma and control group (5.4 ± 0.6 vs. 5.9 ± 0.4; p=0.002) was detected. A negative correlation among brachial FMD and brachial artery diameter at rest was found. Conclusion : Impaired brachial FMD could indicate presence of systemic vascular endothelial dysfunction in patients with glaucoma.

    Cardiologia Croatica
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    Endothelial function in patients with glaucoma

    Extended Abstract
    Issue9-10
    Published
    Pages380
    PDF via DOIhttps://doi.org/10.15836/ccar2017.380
    endothelial function
    flow-mediated dilation
    glaucoma

    Authors

    Duška Glavaš*ORCIDUniversity Hospital Centre Split, Split, Croatia
    Lovre BojićORCIDUniversity Hospital Centre Split, Split, Croatia
    Ratko ErmacoraORCIDUniversity Hospital Centre Split, Split, Croatia
    Bruna BojićORCIDUniversity Hospital Centre Split, Split, Croatia

    Full Text

    Introduction : Cardiovascular illness are more often observed in glaucoma patients. ( 1 ) The purpose of the study was to assess the ultrasound measurements of the brachial artery flow-mediated dilation (FMD) in patients with glaucoma. Patients and Methods : Thirty-seven patients with glaucoma and thirty-one healthy controls were included in the study. All glaucoma patients and controls underwent ultrasound measurement of FMD of the brachial artery. Results : The mean values of brachial FMD were significantly lower among glaucoma group compared with control group (15.3 ± 9.5% vs 19.8 ± 9.3%; p=0.04). No significant difference was found in brachial artery diameter at rest (4.7 ± 0.6 vs. 4.9 ± 0.3; p=0.2) between glaucoma patients and controls. The significant difference in brachial artery diameter in hyperemia between patients with glaucoma and control group (5.4 ± 0.6 vs. 5.9 ± 0.4; p=0.002) was detected. A negative correlation among brachial FMD and brachial artery diameter at rest was found. Conclusion : Impaired brachial FMD could indicate presence of systemic vascular endothelial dysfunction in patients with glaucoma.