Correlation between red cell distribution width, systolic function and atrial fibrillation occurrence in patients with acute ST segment elevation myocardial infarction

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    Keywords

    Red cell distribution width, systolic function, ST segment elevation myocardial infarction

    DOI

    https://doi.org/10.15836/ccar2017.346

    Full Text

    Aim : Red cell distribution width as an indicator of inflammation has been shown as a predictive and prognostic factor in coronary artery disease as well as in heart failure ( 1 , 2 ). The aim of this study was to evaluate correlation between red cell distribution width (RDW) and echocardiographic parameters of systolic FUNCTION and atrial fibrillation occurrence in patients with acute ST segment elevation myocardial infarction (STEMI). Patients and Methods : We recruited 89 patients with acute myocardial infarction with ST elevation who were hospitalized in the Department of Cardiovascular Diseases, University Hospital Dubrava, Zagreb. Complete blood count was determined from blood samples prior to percutaneous coronary intervention (PCI). Echocardiographic exam was performed by two independent experts after PCI. Results : RDW was negatively correlated with ejection fraction (p=0.026, Rho=-0.24), patients with EF <50% had higher RDW values (14.35 vs 13.8%, p=0.009) as well as patients with EF <40% (15.8% vs 13.9%, p=0.008). As expected, TIMI score was correlated with systolic function and RDW values. Patients with higher values of RDW had higher risk of developing atrial fibrillation in the follow- up period (>14.5%, P=0.00, HR=3.99). Conclusion : Increased RDW values on admission in STEMI patients treated with PCI are associated with systolic dysfunction and atrial fibrillation occurrence in the follow -up period. These findings can guide further clinical practice but must be confirmed in future studies with more patients.

    Cardiologia Croatica
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    Correlation between red cell distribution width, systolic function and atrial fibrillation occurrence in patients with acute ST segment elevation myocardial infarction

    Extended Abstract
    Issue9-10
    Published
    Pages346
    PDF via DOIhttps://doi.org/10.15836/ccar2017.346
    Red cell distribution width
    systolic function
    ST segment elevation myocardial infarction

    Authors

    Jasmina Ćatić*ORCIDUniversity Hospital Dubrava, Zagreb, Croatia
    Ivana JurinORCIDUniversity Hospital Dubrava, Zagreb, Croatia
    Marko LucijanićORCIDUniversity Hospital Dubrava, Zagreb, Croatia
    Sandra JakšićUniversity Hospital Dubrava, Zagreb, Croatia
    JurinjakORCIDUniversity Hospital Dubrava, Zagreb, Croatia
    Tomislava BodrožićUniversity Hospital Dubrava, Zagreb, Croatia
    DžakićUniversity Hospital Dubrava, Zagreb, Croatia
    PoljakORCIDUniversity Hospital Dubrava, Zagreb, Croatia
    Robert BlažekovićORCIDUniversity Hospital Dubrava, Zagreb, Croatia

    Full Text

    Aim : Red cell distribution width as an indicator of inflammation has been shown as a predictive and prognostic factor in coronary artery disease as well as in heart failure ( 1 , 2 ). The aim of this study was to evaluate correlation between red cell distribution width (RDW) and echocardiographic parameters of systolic FUNCTION and atrial fibrillation occurrence in patients with acute ST segment elevation myocardial infarction (STEMI). Patients and Methods : We recruited 89 patients with acute myocardial infarction with ST elevation who were hospitalized in the Department of Cardiovascular Diseases, University Hospital Dubrava, Zagreb. Complete blood count was determined from blood samples prior to percutaneous coronary intervention (PCI). Echocardiographic exam was performed by two independent experts after PCI. Results : RDW was negatively correlated with ejection fraction (p=0.026, Rho=-0.24), patients with EF <50% had higher RDW values (14.35 vs 13.8%, p=0.009) as well as patients with EF <40% (15.8% vs 13.9%, p=0.008). As expected, TIMI score was correlated with systolic function and RDW values. Patients with higher values of RDW had higher risk of developing atrial fibrillation in the follow- up period (>14.5%, P=0.00, HR=3.99). Conclusion : Increased RDW values on admission in STEMI patients treated with PCI are associated with systolic dysfunction and atrial fibrillation occurrence in the follow -up period. These findings can guide further clinical practice but must be confirmed in future studies with more patients.