Authors

• Jasmina Ćatić — University Hospital Dubrava, Zagreb, Croatia — ORCID: 0000-0001-6582-4201
• Ivana Jurin — University Hospital Dubrava, Zagreb, Croatia — ORCID: 0000-0002-2637-9691
• Marko Lucijanić — University Hospital Dubrava, Zagreb, Croatia — ORCID: 0000-0002-1372-2040
• Sandra Jakšić — University Hospital Dubrava, Zagreb, Croatia
• Jurinjak — University Hospital Dubrava, Zagreb, Croatia — ORCID: 0000-0002-7349-6137
• Tomislava Bodrožić — University Hospital Dubrava, Zagreb, Croatia
• Džakić — University Hospital Dubrava, Zagreb, Croatia
• Poljak — University Hospital Dubrava, Zagreb, Croatia — ORCID: 0000-0002-7293-3972
• Robert Blažeković — University Hospital Dubrava, Zagreb, Croatia — ORCID: 0000-0001-7125-361X

Abstract

**Aim**: Red cell distribution width as an indicator of inflammation has been shown as a predictive and prognostic factor in coronary artery disease as well as in heart failure (1, 2). The aim of this study was to evaluate correlation between red cell distribution width (RDW) and echocardiographic parameters of systolic FUNCTION and atrial fibrillation occurrence in patients with acute ST segment elevation myocardial infarction (STEMI). **Patients and Methods**: We recruited 89 patients with acute myocardial infarction with ST elevation who were hospitalized in the Department of Cardiovascular Diseases, University Hospital Dubrava, Zagreb. Complete blood count was determined from blood samples prior to percutaneous coronary intervention (PCI). Echocardiographic exam was performed by two independent experts after PCI. **Results**: RDW was negatively correlated with ejection fraction (p=0.026, Rho=-0.24), patients with EF 14.5%, P=0.00, HR=3.99). **Conclusion**: Increased RDW values on admission in STEMI patients treated with PCI are associated with systolic dysfunction and atrial fibrillation occurrence in the follow -up period. These findings can guide further clinical practice but must be confirmed in future studies with more patients.

Keywords

Red cell distribution width, systolic function, ST segment elevation myocardial infarction

DOI

Literature

1. Zalawadiya SK, Veeranna V, Niraj A, Pradhan J, Afonso L. Red cell distribution width and risk of coronary heart disease events. Am J Cardiol. 2010 Oct 1;106(7):988–93. https://doi.org/10.1016/j.amjcard.2010.06.006
2. Uyarel H, Ergelen M, Cicek G, Kaya MG, Ayhan E, Turkkan C, et al. Red cell distribution width as a novel prognostic marker in patients undergoing primary angioplasty for acute myocardial infarction. Coron Artery Dis. 2011 May;22(3):138–44. https://doi.org/10.1097/MCA.0b013e328342c77b