Authors
- Luka Perčin — University of Zagreb School of Medicine, Zagreb, Croatia — ORCID: 0000-0003-0497-6871
- Maja Strozzi — University of Zagreb School of Medicine, Zagreb, Croatia — ORCID: 0000-0003-4596-8261
- Darko Anić — University of Zagreb School of Medicine, Zagreb, Croatia — ORCID: 0000-0002-7378-944X
- Mislav Planinc — University of Zagreb School of Medicine, Zagreb, Croatia — ORCID: 0000-0002-9833-832X
- Goran Međimurec — University of Zagreb School of Medicine, Zagreb, Croatia — ORCID: 0000-0002-9602-7114
- Tomislav Tokić — University of Zagreb School of Medicine, Zagreb, Croatia — ORCID: 0000-0001-6871-8746
- Kristina Marić Bešić — University of Zagreb School of Medicine, Zagreb, Croatia — ORCID: 0000-0002-4004-7271
Keywords
anomalous origin, coronary artery, surgery
DOI
https://doi.org/10.15836/ccar2021.46Full Text
Introduction : An anomalous aortic origin of the left main coronary artery (LMCA) with an inter-arterial or intramural course is a rare but dreadful congenital condition that carries a substantial risk of sudden cardiac death ( 1 , 2 ). It can present with syncope, myocardial infarction, and arrhythmias that can lead to cardiac arrest. Coronary computed tomography angiography (CCTA) is a commonly used imaging method in detecting the anomaly while cardiac surgery is the treatment of choice ( 3 ). Case report : We present a case of a 19-year old female with a medical history of intermittent chest pain and presyncope who was hospitalized at the University Hospital Centre Zagreb due to an out of hospital cardiac arrest followed by successful cardiopulmonary resuscitation. At the admission, she was sedated, intubated, mechanically ventilated and hemodynamically stable. After the conduction of an induced hypothermia protocol, the patient was extubated and awakened without signs of neurological deficit. While both echocardiography exam and the magnetic resonance scan confirmed a structurally normal heart, CCTA showed an anomalous origin of the LMCA from the right coronary sinus with an inter-arterial narrow course between the wall of the ascending aorta and pulmonary artery ( Figure 1 ). Since this finding identified the underlying reason for cardiac arrest, the cardiothoracic surgeon was consulted. The patient subsequently underwent cardiac surgery where it was verified that LMCA courses within the anterior aortic wall ( Figure 2 ). A successful „unroofing procedure“ was performed which consisted of an incision of the intramural segment of LMCA with neo-ostium formation at the left coronary cusp ( Figure 3 ). The patient had an uneventful postoperative period and was discharged without complications. On follow-up, control CCTA confirmed the normal origin and course of LMCA ( Figure 4 ) which correlated with the patient`s excellent performance on cardiac exercise stress testing. Computed tomography coronary angiogram, axial plane. Anomalous origin of left main coronary artery from the right coronary sinus (black arrow). Intraoperative photograph. The right coronary sinus as seen after the aortotomy with the ostium of the right coronary artery (black arrow). The coronary probe is placed inside the intramural course of left main coronary artery (black arrow with interrupted lines). Intraoperative photograph. Left main coronary artery (LMCA) after the unroofing of the intramural portion with neo-ostium of the LMCA in the left coronary sinus (black arrow). Computed tomography coronary angiogram, axial plane. Neo-ostium of the left main coronary artery in the left coronary sinus (black arrow). Conclusion : The main aim of this case report was to emphasize anomalous LMCA origin as an important cause of chest pain, syncope and arrhythmias that can lead to cardiac arrest in young, otherwise healthy patients. Furthermore, we wanted to point out the „unroofing procedure“ as an effective method of anomalous LMCA origin treatment.